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Weight then tends to level off or increase during the remainder of treatment.

Maximum weight loss usually occurs within 6 months of starting medication treatment. Combined drug treatment using fenfluramine and phentermine fen,phen is no longer available due to the withdrawal of fenfluramine from the market. It should be noted that the vast majority of cases of PPH have occurred in patients who were taking fenfluramine or dexfenfluramine, either alone or in combination. Some of these cases involved patients who were taking fenfluramine or dexfenfluramine alone.

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